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编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D151349-0050 | 50 ul | 预计5日内发货 |
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D151349-0100 | 100 ul | 预计7日内发货 |
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D151349-0200 | 200 ul | 预计7日内发货 |
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概述
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
应用
免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | P27708 |
靶点基因 ID | 790 |
靶点全称 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
靶点别名 | CAD |
靶点研究领域 | Epigenetics and Nuclear Signaling, Cancer, Metabolism |
亚型 | Immunogen-specific rabbit IgG |