Order NO. D151349
产品描述
概述
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
应用
免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P27708
|
靶点基因 ID |
790
|
靶点全称 |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
|
靶点别名 |
CAD
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer, Metabolism
|
亚型 |
Immunogen-specific rabbit IgG
|