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Order NO. D151349
兔抗CAD(phospho-Thr456)多克隆抗体
英文名 Anti-CAD (phospho-Thr456) rabbit polyclonal antibody
别名 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; CAD
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 CAD
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D151349-0050 50 ul 预计5日内发货
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D151349-0100 100 ul 预计7日内发货
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D151349-0200 200 ul 预计7日内发货
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产品描述

概述

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

应用

免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P27708
靶点基因 ID 790
靶点全称 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
靶点别名 CAD
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer, Metabolism
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human colon carcinoma tissue using D151349(CAD(Phospho-Thr456) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

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