Order NO. D151366
兔抗MDC1（phospho-Ser513）多克隆抗体
| 英文名 | Anti-MDC1 (phospho-Ser513) rabbit polyclonal antibody | ||
| 别名 | mediator of DNA-damage checkpoint 1; NFBD1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 克隆类型 | rabbit polyclonal | 抗原 | MDC1 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D151366-0050 | 50 ul | 预计5日内发货 |
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| D151366-0100 | 100 ul | 预计7日内发货 |
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| D151366-0200 | 200 ul | 预计7日内发货 |
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产品描述
概述
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
应用
免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q14676 |
| 靶点基因 ID | 9656 |
| 靶点全称 | mediator of DNA-damage checkpoint 1 |
| 靶点别名 | NFBD1 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
