Order NO. D151515
产品描述
概述
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P10721
|
靶点基因 ID |
3815
|
靶点全称 |
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
靶点别名 |
PBT; SCFR; C-Kit; CD117
|
靶点研究领域 |
Signal Transduction, Cancer, Neuroscience, Immunology, Stem Cells, Developmental Biology
|
亚型 |
Immunogen-specific rabbit IgG
|