Order NO. D151526
产品描述
概述
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P19429
|
靶点基因 ID |
7137
|
靶点全称 |
troponin I type 3 (cardiac)
|
靶点别名 |
CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
|
靶点研究领域 |
Signal Transduction,Stem Cells, Cardiovascular, Developmental Biology
|
亚型 |
Immunogen-specific rabbit IgG
|