Order NO. D151616
产品描述
概述
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase.
应用
免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P31749
|
靶点基因 ID |
207
|
靶点全称 |
v-akt murine thymoma viral oncogene homolog 1
|
靶点别名 |
AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
|
亚型 |
Immunogen-specific rabbit IgG
|