Order NO. D151646
产品描述
概述
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene.
应用
免疫印迹(WB),免疫荧光(IF)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q9Y6K9
|
靶点基因 ID |
8517
|
靶点全称 |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
|
靶点别名 |
IP; IP1; IP2; FIP3; IPD2; NEMO; FIP-3; Fip3p; IMD33; AMCBX1; ZC2HC9; IKK-gamma
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|