Order NO. D151766
兔抗SMAD2（Ab-465）多克隆抗体
| 英文名 | Anti-SMAD2 (Ab-465) rabbit polyclonal antibody | ||
| 别名 | SMAD family member 2; JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 克隆类型 | rabbit polyclonal | 抗原 | SMAD2 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D151766-0050 | 50 ul | 预计5日内发货 |
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| D151766-0100 | 100 ul | 预计7日内发货 |
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| D151766-0200 | 200 ul | 预计7日内发货 |
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产品描述
概述
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
应用
免疫印迹（WB）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q15796 |
| 靶点基因 ID | 4087 |
| 靶点全称 | SMAD family member 2 |
| 靶点别名 | JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2 |
| 靶点研究领域 | Signal Transduction, Epigenetics and Nuclear Signaling, Cancer |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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