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Order NO. D151806
兔抗PRKN多克隆抗体
英文名 Anti-PRKN rabbit polyclonal antibody
别名 parkin RBR E3 ubiquitin protein ligase; PDJ; AR-JP; LPRS2; PARK2
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human Mouse Rat
克隆类型 rabbit polyclonal 抗原 PRKN
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D151806-0050 50 ul 预计5日内发货
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D151806-0100 100 ul 预计7日内发货
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D151806-0200 200 ul 预计7日内发货
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产品描述

概述

The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 O60260
靶点基因 ID 5071
靶点全称 parkin RBR E3 ubiquitin protein ligase
靶点别名 PDJ; AR-JP; LPRS2; PARK2
靶点研究领域 Neuroscience, Cell Biology, Metabolism
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using D151806(PRKN Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Jurkat cells lysate, Primary antibody: D151806(PRKN antibody) at dilution 1/500 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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