Order NO. D151806
产品描述
概述
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
O60260
|
靶点基因 ID |
5071
|
靶点全称 |
parkin RBR E3 ubiquitin protein ligase
|
靶点别名 |
PDJ; AR-JP; LPRS2; PARK2
|
靶点研究领域 |
Neuroscience, Cell Biology, Metabolism
|
亚型 |
Immunogen-specific rabbit IgG
|