Order NO. D151913
产品描述
概述
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.
应用
免疫印迹(WB),免疫荧光(IF)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
O95819
|
靶点基因 ID |
9448
|
靶点全称 |
mitogen-activated protein kinase kinase kinase kinase 4
|
靶点别名 |
HGK; NIK; MEKKK4; FLH21957; HEL-S-31
|
靶点研究领域 |
Signal Transduction
|
亚型 |
Immunogen-specific rabbit IgG
|