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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D152516-0050 | 50 ul | 预计5日内发货 | 待询价 | 待询价 | |
D152516-0100 | 100 ul | 预计7日内发货 | 待询价 | 待询价 | |
D152516-0200 | 200 ul | 预计7日内发货 | 待询价 | 待询价 |
概述
Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Zinc finger and SCAN domain-containing protein 16 (ZSCAN16), also known as ZNF392 or ZNF435, is a 348 amino acid member of the Krüppel C2H2-type zinc finger protein family. Localized to the nucleus, ZSCAN16 contains four C2H2-type zinc fingers at the carboxy terminus and one SCAN box domain, a leucine rich region of about 80 amino acids, at the amino terminus through which it is thought to be involved in DNA-binding and transcriptional regulation. ZSCAN16 has been shown to repress reporter gene transcription, and overexpression of ZNF435 also suppressed the transcriptional activities of AP-1μ. Because AP-1μ is activated by MAPK-mediated phosphorylation, ZNF435 is though to be involved in the MAPK pathway.
应用
免疫印迹(WB)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q9H4T2 |
靶点基因 ID | 80345 |
靶点全称 | zinc finger and SCAN domain containing 16 |
靶点别名 | ZNF392; ZNF435; dJ265C24.3 |
靶点研究领域 | Epigenetics and Nuclear Signaling |
亚型 | Immunogen-specific rabbit IgG |

