Order NO. D153116
产品描述
概述
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response.
应用
免疫荧光(IF)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q8NHJ6
|
靶点基因 ID |
11006
|
靶点全称 |
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
|
靶点别名 |
ILT3; LIR5; CD85K; ILT-3; LIR-5
|
靶点研究领域 |
Immunology, Epigenetics and Nuclear Signaling, Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
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