Order NO. D155019
产品描述
概述
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q14765
|
靶点基因 ID |
6775
|
靶点全称 |
signal transducer and activator of transcription 4 (Phospho-Tyr693)
|
靶点别名 |
SLEB11
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling
|
亚型 |
Immunogen-specific rabbit IgG
|