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Order NO. D155026
兔抗Bad (Phospho-Ser136) 多克隆抗体
英文名 Anti-Bad (Phospho-Ser136) rabbit polyclonal antibody
别名 Bbc2; AI325008
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 Bad
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D155026-0025 25 ul 现货
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D155026-0100 100 ul 现货
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D155026-0200 200 ul 现货
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产品描述

概述

The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q61337
靶点基因 ID 572
靶点全称 BCL2-associated agonist of cell death (Phospho-Ser136)
靶点别名 Bbc2; AI325008
靶点研究领域 Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D155026(Bad (Phospho-Ser136) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane 1-2: HT29 cells untreated with UV, HT29 cells treated with UV, Primary antibody: D155026(Bad (Phospho-Ser136) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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