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Order NO. D155039
兔抗TP53 (Phospho-Ser6)多克隆抗体
英文名 Anti-TP53 (Phospho-Ser6) rabbit polyclonal antibody
别名 P53; BCC7; LFS1; TRP53
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 TP53
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D155039-0025 25 ul 现货
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D155039-0100 100 ul 现货
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D155039-0200 200 ul 现货
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产品描述

概述

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P04637
靶点基因 ID 7157
靶点全称 tumor protein p53 (Phospho-Ser6)
靶点别名 P53; BCC7; LFS1; TRP53
靶点研究领域 Cell Biology, Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D155039(TP53 (Phospho-Ser6) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane 1-4: HT29 cells untreated with UV, HT29 cells treated with UV, Hela cells untreated with UV, Hela cells treated with UV, Primary antibody: D155039(TP53 (Phospho-Ser6) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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