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Order NO. D155121
兔抗MAPK14 (Phospho-Tyr182) 多克隆抗体
英文名 Anti-MAPK14 (Phospho-Tyr182) rabbit polyclonal antibody
别名 RP1-179N16.5; CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; P38alpha
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 MAPK14
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D155121-0025 25 ul 现货
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D155121-0100 100 ul 现货
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D155121-0200 200 ul 现货
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产品描述

概述

Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q16539
靶点基因 ID 1432
靶点全称 mitogen-activated protein kinase 14 (Phospho-Tyr182)
靶点别名 RP1-179N16.5; CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; P38alpha
靶点研究领域 Signal Transduction, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D155121(MAPK14 (Phospho-Tyr182) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane 1-3: Hela cells treated with UV for 0 min, 15 min, 30 min, Primary antibody: D155121(MAPK14 (Phospho-Tyr182) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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