Order NO. D155136
产品描述
概述
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
应用
免疫印迹(WB),免疫荧光(IF)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P37840
|
靶点基因 ID |
6622
|
靶点全称 |
synuclein, alpha (non A4 component of amyloid precursor) (Phospho-Tyr136)
|
靶点别名 |
PD1; NACP; PARK1; PARK4
|
靶点研究领域 |
Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|