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Order NO. D155164
兔抗ABL1/ABL2 (phospho-Tyr393/439)多克隆抗体
英文名 Anti-ABL1/ABL2 (phospho-Tyr393/439) rabbit polyclonal antibody
别名 Abelson murine leukemia viral oncogene homolog 1; c-ABL; p150
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 ABL1/ABL2
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D155164-0025 25 ul 现货
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D155164-0100 100 ul 现货
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D155164-0200 200 ul 现货
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产品描述

概述

Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P00519/P42684
靶点基因 ID 25/27
靶点全称 ABL proto-oncogene 1, non-receptor tyrosine kinase/ABL proto-oncogene 2, non-receptor tyrosine kinase
靶点别名 ABL; JTK7; p150; c-ABL; v-abl; CHDSKM; c-ABL1; bcr/abl; ARG; ABLL
靶点研究领域 Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D155164(ABL1/ABL2(phospho-Tyr393/439) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-2: The antibody treated with the peptide, HL60 cells, Primary antibody: D155164(ABL1/ABL2(phospho-Tyr393/439) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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