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Order NO. D155174
兔抗CBL (phospho-Tyr700) 多克隆抗体
英文名 Anti-CBL (phospho-Tyr700) rabbit polyclonal antibody
别名 CBL2; NSLL; C-CBL; RNF55; FRA11B
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 CBL
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D155174-0025 25 ul 现货
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D155174-0100 100 ul 现货
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D155174-0200 200 ul 现货
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产品描述

概述

Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.

应用

免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P22681
靶点基因 ID 867
靶点全称 Cbl proto-oncogene, E3 ubiquitin protein ligase (phospho-Tyr700)
靶点别名 CBL2; NSLL; C-CBL; RNF55; FRA11B
靶点研究领域 Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D155174(CBL (phospho-Tyr700) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-2: HT29 cells untreated with UV , HT29 cells treated with UV , Primary antibody: D155174(CBL (phospho-Tyr700) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

  • The image is immunofluorescence of Hela cells using D155174(CBL (phospho-Tyr700) Antibody) at dilution 1/100.
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