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Order NO. D155180
兔抗ACACA(Phospho-Ser79)多克隆抗体
英文名 Anti-ACACA(Phospho-Ser79) rabbit polyclonal antibody
别名 ACC; ACAC; ACC1; ACCA; ACACAD
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 ACACA
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D155180-0025 25 ul 现货
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D155180-0100 100 ul 现货
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D155180-0200 200 ul 现货
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产品描述

概述

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

应用

免疫印迹(WB)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q13085
靶点基因 ID 31
靶点全称 acetyl-CoA carboxylase alpha (Phospho-Ser79)
靶点别名 ACC; ACAC; ACC1; ACCA; ACACAD
靶点研究领域 Cardiovascular, Metabolism, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-2: 293 cells untreated with AICAR , 293 cells treated with AICAR , Primary antibody: D155180(ACACA (Phospho-Ser80) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute