Order NO. D160102
产品描述
概述
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P11511
|
靶点基因 ID |
1588
|
靶点全称 |
cytochrome P450, family 19, subfamily A, polypeptide 1
|
靶点别名 |
ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer, Metabolism, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|