Order NO. D160125
产品描述
概述
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P08620
|
靶点基因 ID |
2249
|
靶点全称 |
fibroblast growth factor 4
|
靶点别名 |
HST, KFGF, HST-1, HSTF1, K-FGF, HBGF-4
|
靶点研究领域 |
Signal Transduction, Cancer, Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
|