Order NO. D160160
产品描述
概述
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P49918
|
靶点基因 ID |
1028
|
靶点全称 |
cyclin dependent kinase inhibitor 1C
|
靶点别名 |
BWS; WBS; p57; BWCR; KIP2; p57Kip2
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer
|
亚型 |
Immunogen-specific rabbit IgG
|