Order NO. D160165
兔抗ERBB2多克隆抗体
| 英文名 | Anti-ERBB2 rabbit polyclonal antibody | ||
| 别名 | erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | ERBB2 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D160165-0025 | 25 ul | 现货 |
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| D160165-0100 | 100 ul | 现货 |
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| D160165-0200 | 200 ul | 现货 |
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属性
| Background: | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | ERBB2 |
| Immunogen: | Synthetic peptide of human ERBB2 |
| Full name: | erb-b2 receptor tyrosine kinase 2 |
| Synonyms: | NEU; NGL; HER2; TKR1; CD340; HER-2; VSCN2; MLN 19; MLN-19; c-ERB2; c-ERB-2; HER-2/neu; p185(erbB2) |
| SwissProt: | P04626 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human breast cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 138 kDa |
| WB Positive control: | MCF-7 cell lysate |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
