Order NO. D160174
产品描述
概述
Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytosol; and nuclear speck. Part of beta-catenin destruction complex. Colocalizes with keratin filament and mRNA cleavage and polyadenylation specificity factor complex. Biomarker of Alzheimer's disease and inclusion body myositis.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P48729
|
靶点基因 ID |
1452
|
靶点全称 |
casein kinase 1 alpha 1
|
靶点别名 |
CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p
|
靶点研究领域 |
Signal Transduction
|
亚型 |
Immunogen-specific rabbit IgG
|