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Order NO. D160236
兔抗CCND1多克隆抗体
英文名 Anti-CCND1 rabbit polyclonal antibody
别名 BCL1, PRAD1, U21B31, D11S287E
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 CCND1    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D160236-0025 25 ul 现货
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D160236-0100 100 ul 现货
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D160236-0200 200 ul 现货
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属性

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers. [provided by RefSeq, Dec 2019] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, IHC
Name of antibody: CCND1
Immunogen: Synthetic peptide of human CCND1
Full name: cyclin D1
Synonyms: BCL1; PRAD1; U21B31; D11S287E
SwissProt: P24385
ELISA Recommended dilution: 500-5000
IHC positive control: Human breast cancer and Human ovarian cancer
IHC Recommend dilution: 50-200
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D160236(CCND1 Antibody) at dilution 1/50. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using D160236(CCND1 Antibody) at dilution 1/50. (Original magnification: ×200)
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