Order NO. D160588
兔抗MC1R多克隆抗体
| 英文名 | Anti-MC1R rabbit polyclonal antibody | ||
| 别名 | CMM5, MSH-R, SHEP2 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | MC1R | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D160588-0025 | 25 ul | 现货 |
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| D160588-0100 | 100 ul | 现货 |
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| D160588-0200 | 200 ul | 现货 |
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属性
| Background: | This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, WB |
| Name of antibody: | MC1R |
| Immunogen: | Synthetic peptide of human MC1R |
| Full name: | melanocortin 1 receptor |
| Synonyms: | CMM5; MSH-R; SHEP2 |
| SwissProt: | Q01726 |
| ELISA Recommended dilution: | 5000-10000 |
| WB Predicted band size: | 35 kDa |
| WB Positive control: | Mouse brain tissue lysate |
| WB Recommended dilution: | 1000-5000 |
相关文档
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Sample Application
