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Order NO. D160725
兔抗RAD50多克隆抗体
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D160725-0025 | 25 ul | 现货 |
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| D160725-0100 | 100 ul | 现货 |
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| D160725-0200 | 200 ul | 现货 |
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产品描述
概述
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q92878 |
| 靶点基因 ID | 10111 |
| 靶点全称 | RAD50 double strand break repair protein |
| 靶点别名 | NBSLD; RAD502; hRad50 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
Sample Application
