
Order NO. D160746
兔抗SMAD7多克隆抗体




英文名 | Anti-SMAD7 rabbit polyclonal antibody | ||
别名 | CRCS3, MADH7, MADH8 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
抗原 | SMAD7 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D160746-0025 | 25 ul | 现货 |
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D160746-0100 | 100 ul | 现货 |
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D160746-0200 | 200 ul | 现货 |
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属性
Background: | The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] (The background information is obtained from official databases and does not represent the product information.) |
Applications: | ELISA, WB, IHC |
Name of antibody: | SMAD7 |
Immunogen: | Synthetic peptide of human SMAD7 |
Full name: | SMAD family member 7 |
Synonyms: | CRCS3; MADH7; MADH8 |
SwissProt: | O15105 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human breast cancer and Human prostate cancer |
IHC Recommend dilution: | 50-200 |
WB Predicted band size: | 46 kDa |
WB Positive control: | Mouse liver tissue lysate |
WB Recommended dilution: | 1000-5000 |