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Order NO. D160746
兔抗SMAD7多克隆抗体
英文名 Anti-SMAD7 rabbit polyclonal antibody
别名 CRCS3, MADH7, MADH8
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 SMAD7    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D160746-0025 25 ul 现货
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D160746-0100 100 ul 现货
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D160746-0200 200 ul 现货
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属性

Background: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, WB, IHC
Name of antibody: SMAD7
Immunogen: Synthetic peptide of human SMAD7
Full name: SMAD family member 7
Synonyms: CRCS3; MADH7; MADH8
SwissProt: O15105
ELISA Recommended dilution: 5000-10000
IHC positive control: Human breast cancer and Human prostate cancer
IHC Recommend dilution: 50-200
WB Predicted band size: 46 kDa
WB Positive control: Mouse liver tissue lysate
WB Recommended dilution: 1000-5000
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D160746(SMAD7 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using D160746(SMAD7 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue lysate, Primary antibody: D160746(SMAD7 Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 30 seconds
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