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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D160943-0025 | 25 ul | 现货 | 待询价 | 待询价 | |
D160943-0100 | 100 ul | 现货 | 待询价 | 待询价 | |
D160943-0200 | 200 ul | 现货 | 待询价 | 待询价 |
概述
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q8ND04 |
靶点基因 ID | 55181 |
靶点全称 | SMG8 nonsense mediated mRNA decay factor |
靶点别名 | C17orf71 |
靶点研究领域 | Cancer |
亚型 | Immunogen-specific rabbit IgG |

