在线客服
网站反馈
网站指南
我的草稿
我的购物车
Order NO. D160943
兔抗SMG8多克隆抗体
英文名 Anti-SMG8 rabbit polyclonal antibody
别名 C17orf71
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 SMG8
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D160943-0025 25 ul 现货 待询价 待询价
+
加入购物车
D160943-0100 100 ul 现货 待询价 待询价
+
加入购物车
D160943-0200 200 ul 现货 待询价 待询价
+
加入购物车
产品描述

概述

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q8ND04
靶点基因 ID 55181
靶点全称 SMG8 nonsense mediated mRNA decay factor
靶点别名 C17orf71
靶点研究领域 Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using D160943(SMG8 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using D160943(SMG8 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)