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Order NO. D160963
兔抗ANPEP多克隆抗体
英文名 Anti-ANPEP rabbit polyclonal antibody
别名 APN; CD13; LAP1; P150; PEPN; GP150
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 ANPEP
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D160963-0025 25 ul 现货 待询价 待询价
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D160963-0100 100 ul 现货 待询价 待询价
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D160963-0200 200 ul 现货 待询价 待询价
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产品描述

概述

Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P15144
靶点基因 ID 290
靶点全称 alanyl (membrane) aminopeptidase
靶点别名 APN; CD13; LAP1; P150; PEPN; GP150
靶点研究领域 Immunology, Stem Cells
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using D160963(ANPEP Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using D160963(ANPEP Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)