Order NO. D161007
兔抗MUC16多克隆抗体
| 英文名 | Anti-MUC16 rabbit polyclonal antibody | ||
| 别名 | CA125 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | MUC16 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D161007-0025 | 25 ul | 现货 |
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| D161007-0100 | 100 ul | 现货 |
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| D161007-0200 | 200 ul | 现货 |
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属性
| Background: | This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. |
| Applications: | ELISA, IHC |
| Name of antibody: | MUC16 |
| Immunogen: | Synthetic peptide of human MUC16 |
| Full name: | mucin 16, cell surface associated |
| Synonyms: | CA125 |
| SwissProt: | Q8WXI7 |
| ELISA Recommended dilution: | 2000-5000 |
| IHC positive control: | Human ovarian cancer and Human bladder cancer |
| IHC Recommend dilution: | 25-100 |
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