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Order NO. D161071
兔抗PARP1多克隆抗体
英文名 Anti-PARP1 rabbit polyclonal antibody
别名 PARP, PPOL, ADPRT, ARTD1, ADPRT1, PARP-1, ADPRT 1, pADPRT-1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 PARP1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D161071-0025 25 ul 现货
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D161071-0100 100 ul 现货
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D161071-0200 200 ul 现货
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产品描述

概述

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P09874
靶点基因 ID 142
靶点全称 poly(ADP-ribose) polymerase 1
靶点别名 PARP; PARS; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; Poly-PARP
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D161071(PARP1 Antibody) at dilution 1/20. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D161071(PARP1 Antibody) at dilution 1/20. (Original magnification: ×200)

  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: K562, Hela, Jurkat, A549 cell lysates, Primary antibody: D161071(PARP1 Antibody) at dilution 1/500, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 10 seconds
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