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Order NO. D161214
兔抗RBFOX1多克隆抗体
英文名 Anti-RBFOX1 rabbit polyclonal antibody
别名 2BP1; FOX1; A2BP1; FOX-1; HRNBP1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 RBFOX1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D161214-0025 25 ul 现货
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D161214-0100 100 ul 现货
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D161214-0200 200 ul 现货
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产品描述

概述

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q9NWB1
靶点基因 ID 54715
靶点全称 RNA binding fox-1 homolog 1
靶点别名 2BP1; FOX1; A2BP1; FOX-1; HRNBP1
靶点研究领域 Epigenetics and Nuclear Signaling, Neuroscience, Developmental Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D161214(RBFOX1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using D161214(RBFOX1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T and SKOV3 cell lysates, Primary antibody: D161214(RBFOX1 Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 1 minute
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