Order NO. D161412
兔抗PFKFB4多克隆抗体
| 英文名 | Anti-PFKFB4 rabbit polyclonal antibody | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | PFKFB4 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D161412-0025 | 25 ul | 现货 |
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| D161412-0100 | 100 ul | 现货 |
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| D161412-0200 | 200 ul | 现货 |
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产品描述
概述
The protein encoded by this gene is one of four bifunctional kinase/phosphatases that regulate the concentration of the glycolytic byproduct fructose-2,6-bisphosphate (F2,6BP). The encoded protein is highly expressed in cancer cells and is induced by hypoxia. This protein is essential to the survival of cancer cells under conditions of hypoxia, because it increases the amount of F2,6BP and ATP at a time when the cell cannot produce much of them. This finding suggests that this protein may be a good target for disruption in cancer cells, hopefully imperiling their survival. Several transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q16877 |
| 靶点基因 ID | 5210 |
| 靶点全称 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| 靶点研究领域 | Metabolism, Cancer |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
