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编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D161438-0025 | 25 ul | 现货 |
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D161438-0100 | 100 ul | 现货 |
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D161438-0200 | 200 ul | 现货 |
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概述
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q3V6T2 |
靶点基因 ID | 55704 |
靶点全称 | coiled-coil domain containing 88A |
靶点别名 | APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212 |
靶点研究领域 | Signal Transduction, Neuroscience |
亚型 | Immunogen-specific rabbit IgG |