Order NO. D161599
产品描述
概述
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q9Y6A2
|
靶点基因 ID |
10858
|
靶点全称 |
cytochrome P450 family 46 subfamily A member 1
|
靶点别名 |
CP46; CYP46
|
靶点研究领域 |
Metabolism, Cancer, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|