Order NO. D161600
兔抗CYP2D6多克隆抗体
| 英文名 | Anti-CYP2D6 rabbit polyclonal antibody | ||
| 别名 | CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | CYP2D6 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D161600-0025 | 25 ul | 现货 |
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| D161600-0100 | 100 ul | 现货 |
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| D161600-0200 | 200 ul | 现货 |
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属性
| Background: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, IHC |
| Name of antibody: | CYP2D6 |
| Immunogen: | Synthetic peptide of human CYP2D6 |
| Full name: | cytochrome P450 family 2 subfamily D member 6 |
| Synonyms: | CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1 |
| SwissProt: | P10635 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human liver cancer |
| IHC Recommend dilution: | 50-200 |
相关文档
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Sample Application
