Order NO. D161765
兔抗HSD17B1多克隆抗体
| 英文名 | Anti-HSD17B1 rabbit polyclonal antibody | ||
| 别名 | HSD17; EDHB17; EDH17B2; SDR28C1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 克隆类型 | rabbit polyclonal | 抗原 | HSD17B1 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D161765-0025 | 25 ul | 现货 |
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| D161765-0100 | 100 ul | 现货 |
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| D161765-0200 | 200 ul | 现货 |
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产品描述
概述
Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P14061 |
| 靶点基因 ID | 3292 |
| 靶点全称 | hydroxysteroid (17-beta) dehydrogenase 1 |
| 靶点别名 | HSD17; EDHB17; EDH17B2; SDR28C1 |
| 靶点研究领域 | Metabolism, Signal Transduction, Cancer, Neuroscience |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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