Order NO. D161777
产品描述
概述
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P11717
|
靶点基因 ID |
3482
|
靶点全称 |
insulin-like growth factor 2 receptor
|
靶点别名 |
MPR1; MPRI; CD222; CIMPR; M6P-R
|
靶点研究领域 |
Signal Transduction, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|