Order NO. D161937
产品描述
概述
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P59044
|
靶点基因 ID |
171389
|
靶点全称 |
NLR family pyrin domain containing 6
|
靶点别名 |
AVR; NAVR; PAN3; NALP6; PYPAF5; CLR11.4; NAVR/AVR
|
靶点研究领域 |
Signal Transduction, Cancer, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|