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Order NO. D162134
兔抗RNF139多克隆抗体
英文名 Anti-RNF139 rabbit polyclonal antibody
别名 RCA1; TRC8; HRCA1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 RNF139
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D162134-0025 25 ul 现货
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D162134-0100 100 ul 现货
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D162134-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q8WU17
靶点基因 ID 11236
靶点全称 ring finger protein 139
靶点别名 RCA1; TRC8; HRCA1
靶点研究领域 Cancer, Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D162134(RNF139 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using D162134(RNF139 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)

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