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Order NO. D162451
兔抗UGT1A4多克隆抗体
英文名 Anti-UGT1A4 rabbit polyclonal antibody
别名 UDPGT; UGT1D; UGT-1D; UGT1.4; HUG-BR2; UGT1-04; UDPGT 1-4
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 UGT1A4
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D162451-0025 25 ul 现货
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D162451-0100 100 ul 现货
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D162451-0200 200 ul 现货
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产品描述

概述

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P22310
靶点基因 ID 54657
靶点全称 UDP glucuronosyltransferase family 1 member A4
靶点别名 GNT1; UGT1; UDPGT; UGT1A; UGT1D; UGT-1A; UGT-1D; UGT1.1; UGT1.4; UGT1A1; HUG-BR2; UGT1-01; UGT1-04; UGT1A4S; hUG-BR1; UDPGT 1-4
靶点研究领域 Metabolism, Signal Transduction, Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using D162451(UGT1A4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal intestines tissue and Human liver cancer tissue lysates, Primary antibody: D162451(UGT1A4 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes
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