Order NO. D162769
产品描述
概述
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P28223
|
靶点基因 ID |
3356
|
靶点全称 |
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
|
靶点别名 |
HTR2; 5-HT2A
|
靶点研究领域 |
Metabolism, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|