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Order NO. D162939
兔抗IFITM1多克隆抗体
英文名 Anti-IFITM1 rabbit polyclonal antibody
别名 9-27; CD225; IFI17; LEU13; DSPA2a
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 IFITM1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D162939-0025 25 ul 现货
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D162939-0100 100 ul 现货
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D162939-0200 200 ul 现货
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产品描述

概述

Interferons (IFNs) are potential antitumor agents, as they exhibit antiproliferative and differentiating properties, in addition to functioning in the defense against microbial infections. IFN exposure induces the regulation of expression levels of cellular proteins that mediate the pleiotropic effects of interferons. These effects may be mediated by soluble factors or by cell-cell interactions involving specific membrane proteins. The IFITM family of proteins are transmembrane proteins so named because their expression is IFN-inducible. IFITM proteins have been found upregulated in human colorectal carcinomas. Both mouse IFITM1 (also known as CD225) and IFITM3 demonstrate expression on the cell surfaces of primordial germ cells in a developmentally-regulated manner. They presumably modulate cell adhesion and influence cell differentiation. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P13164
靶点基因 ID 8519
靶点全称 interferon induced transmembrane protein 1
靶点别名 9-27; CD225; IFI17; LEU13; DSPA2a
靶点研究领域 Signal Transduction, Cancer, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D162939(IFITM1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D162939(IFITM1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

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