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Order NO. D163697
兔抗FBXO32多克隆抗体
编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D163697-0025 | 25 ul | 现货 |
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D163697-0100 | 100 ul | 现货 |
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D163697-0200 | 200 ul | 现货 |
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属性
Background: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Applications: | ELISA, IHC |
Name of antibody: | FBXO32 |
Immunogen: | Synthetic peptide of human FBXO32 |
Full name: | F-box protein 32 |
Synonyms: | Fbx32; MAFbx |
SwissProt: | Q969P5 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human skeletal muscle |
IHC Recommend dilution: | 50-100 |
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