Order NO. D163947
兔抗FUBP1多克隆抗体
英文名 | Anti-FUBP1 rabbit polyclonal antibody | ||
别名 | far upstream element binding protein 1; FBP; FUBP; hDH V | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
抗原 | FUBP1 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D163947-0025 | 25 ul | 现货 |
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D163947-0100 | 100 ul | 现货 |
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D163947-0200 | 200 ul | 现货 |
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属性
Background: | The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] (The background information is obtained from official databases and does not represent the product information.) |
Applications: | ELISA, WB, IHC |
Name of antibody: | FUBP1 |
Immunogen: | Synthetic peptide of human FUBP1 |
Full name: | far upstream element binding protein 1 |
Synonyms: | FBP; FUBP; hDH V |
SwissProt: | Q96AE4 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human breast cancer and Human tonsil |
IHC Recommend dilution: | 50-200 |
WB Predicted band size: | 68 kDa |
WB Positive control: | Raji and Jurkat cell lysates |
WB Recommended dilution: | 1000-5000 |