网 站
反 馈
网 站
指 南
Order NO. D163947
兔抗FUBP1多克隆抗体
英文名 Anti-FUBP1 rabbit polyclonal antibody
别名 far upstream element binding protein 1; FBP; FUBP; hDH V
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 FUBP1    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D163947-0025 25 ul 现货
加入购物车
D163947-0100 100 ul 现货
加入购物车
D163947-0200 200 ul 现货
加入购物车

属性

Background: The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, WB, IHC
Name of antibody: FUBP1
Immunogen: Synthetic peptide of human FUBP1
Full name: far upstream element binding protein 1
Synonyms: FBP; FUBP; hDH V
SwissProt: Q96AE4
ELISA Recommended dilution: 5000-10000
IHC positive control: Human breast cancer and Human tonsil
IHC Recommend dilution: 50-200
WB Predicted band size: 68 kDa
WB Positive control: Raji and Jurkat cell lysates
WB Recommended dilution: 1000-5000
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D163947(FUBP1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D163947(FUBP1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Raji and Jurkat cell lysates, Primary antibody: D163947(FUBP1 Antibody) at dilution 1/1200, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 5 seconds
    我的购物车(0) 结算