Order NO. D164557
兔抗CDKN2B多克隆抗体
| 英文名 | Anti-CDKN2B rabbit polyclonal antibody | ||
| 别名 | cyclin dependent kinase inhibitor 2B; P15; MTS2; TP15; CDK4I; INK4B; p15INK4b | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 克隆类型 | rabbit polyclonal | 抗原 | CDKN2B |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D164557-0025 | 25 ul | 现货 |
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| D164557-0100 | 100 ul | 现货 |
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| D164557-0200 | 200 ul | 现货 |
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产品描述
概述
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P42772 |
| 靶点基因 ID | 1030 |
| 靶点全称 | cyclin dependent kinase inhibitor 2B |
| 靶点别名 | P15; MTS2; TP15; CDK4I; INK4B; p15INK4b |
| 靶点研究领域 | Cancer, Epigenetics and Nuclear Signaling, Signal Transduction |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
