Order NO. D164676
兔抗CDC42多克隆抗体
| 英文名 | Anti-CDC42 rabbit polyclonal antibody | ||
| 别名 | cell division cycle 42; TKS; G25K; CDC42Hs | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | CDC42 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D164676-0025 | 25 ul | 现货 |
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| D164676-0100 | 100 ul | 现货 |
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| D164676-0200 | 200 ul | 现货 |
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属性
| Background: | The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | CDC42 |
| Immunogen: | Synthetic peptide of human CDC42 |
| Full name: | cell division cycle 42 |
| Synonyms: | TKS; G25K; CDC42Hs |
| SwissProt: | P60953 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human ovarian cancer and Human bladder cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 21 kDa |
| WB Positive control: | Mouse liver tissue lysate |
| WB Recommended dilution: | 1000-5000 |
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