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Order NO. D190662
小鼠抗SIRT6单克隆抗体
英文名 Anti-SIRT6 mouse monoclonal antibody
别名 sirtuin 6; SIR2L6
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat, Monkey
克隆类型 Mouse Monoclonal 抗原 SIRT6
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D190662-0050 50 ul 预计5日内发货
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D190662-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.

应用

免疫印迹(WB),免疫荧光(IF),免疫沉淀(IP)

属性

保存缓冲液 -20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q8N6T7
靶点基因 ID 51548
靶点全称 sirtuin 6
靶点别名 SIR2L6
靶点研究领域 Epigenetics and Nuclear Signaling, Signal Transduction, Metabolism, Cardiovascular
亚型 IgG1
Sample Application

  • The image is immunofluorescence of Hela cells fixed fixed by 4% paraformaldehyde using D190662(SIRT6 Antibody) at dilution 1/100.

  • Immunoprecipitation analysis of Hela cell lysates using D190662(SIRT6 Antibody).

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-8: Jurkat, MCF7, HCT116, K562, COS7, C2C12, 3T3 and Hela cell lysates, Primary antibody: D190662(SIRT6 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes
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