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Order NO. D190662
小鼠抗SIRT6单克隆抗体
英文名 Anti-SIRT6 mouse monoclonal antibody
别名 sirtuin 6; SIR2L6
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat, Monkey
克隆类型 Mouse Monoclonal 抗原 SIRT6
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D190662-0050 50 ul 预计5日内发货
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D190662-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.

应用

免疫印迹(WB),免疫荧光(IF),免疫沉淀(IP)

属性

亚型 IgG1
靶点研究领域 Epigenetics and Nuclear Signaling, Signal Transduction, Metabolism, Cardiovascular
靶点别名 SIR2L6
靶点全称 sirtuin 6
靶点基因 ID 51548
靶点 Uniprot 登记号 Q8N6T7
运输条件 2-8°C
保存缓冲液 -20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
Sample Application

  • The image is immunofluorescence of Hela cells fixed fixed by 4% paraformaldehyde using D190662(SIRT6 Antibody) at dilution 1/100.

  • Immunoprecipitation analysis of Hela cell lysates using D190662(SIRT6 Antibody).

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-8: Jurkat, MCF7, HCT116, K562, COS7, C2C12, 3T3 and Hela cell lysates, Primary antibody: D190662(SIRT6 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes
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