Order NO. D190673
产品描述
概述
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
应用
免疫印迹（WB），免疫荧光（IF）
属性
| 保存缓冲液 |
-20°C, buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
Q9UHK6
|
| 靶点基因 ID |
23600
|
| 靶点全称 |
alpha-methylacyl-CoA racemase
|
| 靶点别名 |
RM; RACE; CBAS4; P504S; AMACRD
|
| 靶点研究领域 |
Metabolism, Epigenetics and Nuclear Signaling, Cancer
|
| 亚型 |
IgG1
|
